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观察94名妇女使用Mesigyna或Cyelofem 9mo后其血浆中纤溶酶原活化物抑制因子(PAI)的活性变化,并与口服低剂量避孕药的妇女作比较。结果显示注射用药的妇女PAI在用药期间略有升高,但变化处在正常范围内,且停药3个月后恢复至用药前水平,这些改变与口服用药的妇女相比较没有统计学意义。说明Mesigyna和Cyelofem作为生育控制是安全的。
Changes in plasma plasminogen activator inhibitor (PAI) activity in 94 women following Mesigyna or Cyelofem 9mo were observed and compared with those of women taking oral low-dose contraceptives. The results showed that women injected with PAI slightly increased during the medication, but the changes in the normal range, and withdrawal 3 months after the return to pre-medication levels, these changes compared with oral administration of women compared with no statistically significant. Show that Mesigyna and Cyelofem are safe as birth control.