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目的:观察天麻钩藤饮联合硝苯地平控释片治疗高血压的疗效。方法:对照组42例服用硝苯地平控释片30 mg·d~(-1)。观察组42例在对照组基础上加用天麻钩藤饮400 ml·d~(-1)。两组疗程均为8周。比较两组治疗前后24 h白昼、夜间各血压均值,以及24 h平均血压负荷值。结果:治疗后,两组患者24 h平均血压(收缩压、舒张压)、白昼血压(收缩压、舒张压)、夜间血压(收缩压、舒张压)、血压负荷值(收缩压、舒张压)均较治疗前明显下降(P<0.05),且治疗后观察组各项指标与对照组相比,差异有统计学意义(P<0.05)。两组均未发生严重不良反应。结论:天麻钩藤饮联合硝苯地平控释片能有效治疗高血压。
Objective: To observe the efficacy of Tianma Gouteng Decoction combined with nifedipine GITS in the treatment of hypertension. Methods: The control group of 42 nifedipine controlled release tablets 30 mg · d ~ (-1). 42 cases in the observation group were given Tianma Gouteng Decoction 400 ml · d ~ (-1) on the basis of the control group. The two groups were treated for 8 weeks. The mean values of blood pressure at 24 h before and after treatment were compared between the two groups during the day and night, and the mean blood pressure at 24 h was compared. Results After treatment, mean blood pressure (systolic pressure and diastolic pressure), blood pressure (systolic pressure and diastolic pressure), nocturnal blood pressure (systolic pressure and diastolic pressure), blood pressure load (systolic and diastolic blood pressure) (P <0.05). Compared with the control group, the indexes in the observation group after treatment were significantly different (P <0.05). No serious adverse reactions occurred in both groups. Conclusion: Tianma Gouteng Decoction combined with nifedipine GITS can effectively treat hypertension.