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目的对肝硬化患者与正常人血浆中PCT、内毒素及细胞间粘附分子-1等指标进行比较,探讨这些指标与肝硬化之间的关系.方法随机选取30位肝硬化患者及30位正常人的血浆进行PCT,ET及sICAM-1水平进行测定.结果与对照组相比,随着病情严重程度,肝硬化患者血浆PCT、内毒素、sICAM-1水平均显著增高.结论肝硬化患者血浆水平与肝硬化患者的严重程度密切相关,它们在致肝组织病变持续加重过程中均具有重要作用.
Objective To compare the plasma PCT, endotoxin and intercellular adhesion molecule-1 in patients with cirrhosis and normal subjects and to explore the relationship between these indicators and cirrhosis.Methods Thirty patients with cirrhosis and 30 normal The plasma levels of PCT, ET and sICAM-1 in human plasma were measured.Results Compared with the control group, the levels of PCT, endotoxin and sICAM-1 in patients with cirrhosis were significantly increased with the severity of the disease.Conclusion The plasma levels of plasma The level is closely related to the severity of patients with cirrhosis, and they play an important role in the pathogenesis of liver lesions.