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棉酚与低血钾症的关系,一直是个悬而未决的问题。这影响到它作为男用节育药的推广应用。我们用本实验室制造的由醋酸去氧皮质酮引起大鼠低血钾的模型,观察棉酚对之是否有影响。结果表明,在本实验条件下,未能证实棉酚与低血钾症有关。
The relationship between gossypol and hypokalemia has always been an open question. This affects its application as a male birth control medicine. We used the model of rat hypokalemia induced by deoxycorticosterone acetate manufactured in our laboratory to observe whether gossypol has any effect on it. The results showed that gossypol was not associated with hypokalemia under this experimental condition.