In this work,the quercetin imprinted core-shell microspheres were prepared using silica surface imprinting technique.A simple sol-gel procedure was used for the synthesis of the imprinted materials with 3-aminopropyltriethoxysilane as functional monomer and tetraethyl orthosilicate as crosslinker.The SEM images indicated that the MIPs shell was successfully grafted onto the silica surface.The characteristics of the molecularly imprinted polymers such as capacity,selectivity and absorption dynamic were investigated by rebinding experiments.The results showed that the prepared MIPs had good imprinting effect and adsorption amount of quercetin.