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目的:分析甲氨蝶呤及米非司酮联合应用于异位妊娠治疗中的效果。方法:选取2010年5月-2013年5月收治的异位妊娠患者60例,分为3组,治疗组采用甲氨蝶呤及米非司酮联合治疗,对照A组单用甲氨蝶呤治疗,对照B组单用米非司酮治疗,对比三组治疗后血HGG恢复时间与住院时间、临床效果以及不良反应情况。结果:治疗组血HGG恢复时间及住院时间均明显更短;治疗组治愈率85.0%,对照A组治愈率65.0%,对照B组治愈率63.3%;另外,三组治疗中均未见明显不良反应;治疗组效果整体更优(P<0.05)。结论:甲氨蝶呤及米非司酮联合应用于异位妊娠治疗中,效果显著,安全性高,临床可广泛应用。
Objective: To analyze the effect of combination of methotrexate and mifepristone in the treatment of ectopic pregnancy. Methods: Sixty patients with ectopic pregnancy who were admitted from May 2010 to May 2013 were divided into three groups. The treatment group was treated with methotrexate and mifepristone. The control group A was given methotrexate alone The patients in control group B were treated with mifepristone alone. The recovery time, hospital stay, clinical effect and adverse reactions of blood HGG in the three groups were compared. Results: The recovery time and hospital stay of HGG in the treatment group were significantly shorter. The cure rate was 85.0% in the treatment group, 65.0% in the control group A and 63.3% in the control group B. In addition, no obvious adverse reactions were found in the three groups Response; the treatment group overall better (P <0.05). Conclusion: Combination of methotrexate and mifepristone in the treatment of ectopic pregnancy has significant effect, high safety and clinical application.