选用免32只,手术截除桡骨2cm。缺损区充填DGB,手术后2、3、6、9周分别杀死动物作光镜及电镜观察。结果在电镜下发现有三类细胞,即成骨系、破基质系细胞和血管内皮细胞,并见到非成骨性结缔组织的间充质细胞分化为前成骨细胞→成骨细胞→骨细胞以及其同时分化为血管内皮细胞的全部过程。表实验从组织学和细胞学二方面证实DGB确有诱导成骨的作用。 Use free 32, surgical excision of the radius 2cm. Defect area filled with DGB, 2,3,6,9 weeks after surgery animals were killed for light and electron microscopy. Results Three types of cells were found under electron microscope, ie, osteogenic, stromal cells and vascular endothelial cells. Mesenchymal cells of non-osteogenic connective tissue were found to differentiate into pre-osteoblast → osteoblast → osteoblast As well as its entire process of differentiation into vascular endothelial cells. The experimental results from histology and cytology confirmed that DGB did induce osteogenesis.