用家蝇作为实验昆虫，测定了４０个芳香羧酸衍生物的驱避活性，并对其结果进行了定量构效关系的研究。结果显示，化合物Ｂ６、Ｂ８、Ｍ２、Ｅ６具有较高的驱避活性；沸点参数Ｂ是影响化合物驱避活性的主要因素。而化合物取代基的体积不应大于苯；取代基的亲脂性（ｌｏｇＰ）应在３．５０左右。 Houseflies were used as experimental insects. The repellent activities of 40 aromatic carboxylic acid derivatives were determined and their QSARs were studied. The results showed that the compounds B6, B8, M2, E6 have higher repellent activity; the boiling point parameter B is the main factor that affects the compound repellent activity. While the volume of compound substituents should not be greater than benzene; the lipophilicity of the substituent (logP) should be around 3.50.