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本文报道药物配伍禁忌的基本规律并例举了一些实例。两种或两种以上药物配合时(最通常是溶液制剂,特别是输液,混合注射液),由于药物相互作用有可能发生治疗作用改变的危险。药物相互作用可导致作用增强、减弱甚至全部丧失,也可能出现一种新产生的作用,甚至是有毒作用。配伍禁忌的发生可以通过浑浊、沉淀、变色或产生气体等现象而被察觉,但也可能是假象,即不出现可察觉的外观,这就容易造成危险。发生配伍禁忌的重要原因有:
This article reports the basic rules of incompatibility of drugs and gives some examples. When two or more drugs are combined (most often in the form of solutions, especially infusions, mixed injections), there is a risk that the therapeutic effect may change due to the drug interaction. Drug interactions can lead to enhanced, diminished or even total loss, may also have a new role, or even toxic effects. Compatibility Contraindications can be detected by phenomena such as turbidity, sedimentation, discoloration or gas generation, but they can also be false, that is, without perceptible appearance, which is easily dangerous. Important reasons for the occurrence of compatibility taboo: