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鹤草酚(Agrlmophol)为中药仙鹤草(Agrimonia Pilosa Lebed.)根芽的提取物,有促使动物体内血吸虫移行入肝和杀死血吸虫成虫的作用。后一作用在中药试验治疗血吸虫病时尚属首次发现。但鹤草酚治疗小白鼠血吸虫病的疗效不高,不适宜于单独使用,当和小剂量的合成药物硝唑咪共同使用时,则明显提高了治疗动物血吸虫病的效果,病犬的雌虫减少率可达98～100％。鹤草酚的毒性症状主要表现在肠胃道及神经系统反应,应用较大剂量时可使家犬双目失明,病理观察也证明了上述损害,但猕猴口服大剂量鹤草酚,除产生肠胃道反应外并未发现视力障碍。
Agrlmophol is an extract from the root bud of Agrimonia Pilosa Lebed. It has the effect of promoting schistosomiasis migration into the liver and killing adult worms of schistosomes. The latter role in the experimental treatment of schistosomiasis is the first time found. However, oxycodone treatment of mice schistosomiasis efficacy is not high, not suitable for use alone, when combined with a small dose of synthetic drugs nitazoxan significantly improved the effect of treatment of schistosomiasis in dogs, reduce female dogs The rate of up to 98 ~ 100%. Toxicity of oxybenzene mainly in the gastrointestinal tract and nervous system response, the application of larger doses can make domestic dogs blind, pathological observation also proved that the above damage, but the cynomolgus monkey oral dose of calamine, in addition to gastrointestinal No visual impairment was found outside the reaction.