高血脂是目前已肯定的致动脉粥样硬化(Atherosclerosis简称AS)的危险因素之一。本文的第一部分观察离体培养的动脉平滑肌细胞(SMC)经高脂血清作用后,和高脂膳食建立的AS斑块段细胞(PSC)的形态变化。第二部分的实验将分析高脂血清影响下的动脉SMC和PSC合成蛋白质功能的变化,以及这些细胞回复用正常血清培养后,其合成蛋白质功能是否有逆转正常的可能,以此探讨运用离体细胞研究AS消退机理的可能 Hyperlipidemia is one of the risk factors of Atherosclerosis (AS). In the first part of this article, we observed the morphological changes of ASC cultured in vitro in hyperlipidemic serum and cultured in high fat diet. The second part of the experiment will analyze changes in the function of SMC and PSC synthetic proteins under the influence of hyperlipidemic serum and the possibility of reversing the function of the synthesized protein after these cells are recovered from normal serum culture. Cells study the possible mechanism of AS regression