随着人们对乳腺癌生物学行为了解的加深,全身治疗的有效性显著提高,远处转移风险降低,局部/区域的复发风险也得到很好地控制。前瞻性随机研究及源于数据库的长期随访结果显示,保乳手术患者的总生存和乳腺癌特异性生存率均与全乳切除一致~([1])。传统观点认为,肿瘤较大、位置特殊的乳房病灶不适合 With the deepening of people’s understanding of the biological behavior of breast cancer, the effectiveness of systemic treatment significantly increased, the risk of distant metastases decreased, local / regional recurrence risk is also well controlled. Prospective, randomized studies and long-term follow-up from databases indicate that total survival and breast cancer-specific survival in patients undergoing breast-conserving surgery are consistent with resection of the complete breast (1). The traditional view that the tumor is larger, the location of special breast lesions are not suitable