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在国外,雌激素是治疗雄激素非依赖性前列腺癌(androgen-independent prostate cancer,AIPCa)的常用药物,而国内尚未见相关报道。我们自2000年2月—2005年1月,用已烯雌酚治疗12例 AIPCa 患者,取得了较好疗效,现报道如下。资料与方法1.临床资料:本组12例患者,年龄68～90岁,平均77.8岁。病程7～61个月,平均30.4个月。所有病例经病理证实为前列腺癌,其中 G_2 3例、G_3 9例。Whitmore-Jewett 临床分期:C 期2例;D 期10例,其中有骨转移9例,在9例中有骨痛5例。按主诉疼痛程度分级法(VRS)将有骨痛5例
Abroad, estrogen is a commonly used drug for the treatment of androgen-independent prostate cancer (AIPCa), but no relevant reports have been reported in China. We from February 2000 -2005 in January, with diethylstilbestrol treatment of 12 patients with AIPCa, and achieved good results, are reported below. Materials and Methods 1. Clinical data: The group of 12 patients, aged 68 to 90 years, mean 77.8 years. Duration of 7 to 61 months, an average of 30.4 months. All cases were pathologically confirmed as prostate cancer, including G_2 3 cases, G_3 9 cases. Whitmore-Jewett clinical stage: 2 cases in stage C; 10 cases in stage D, including 9 cases of bone metastases, 5 cases of bone pain in 9 cases. According to the main complaint of pain level grading (VRS) there will be 5 cases of bone pain