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~(131)I-MIBG(~(131)I-间位碘代苄胍)是一种生物胺前身物的类似物。为了评价它在诊断治疗类癌中的作用,作者用~(131)I-MIBG对20例类癌患者进行了显像,并用此药对5例病人进行了治疗。病人和方法:20例类癌患者都经病理学证实,其中7人有转移病灶而原发灶不明,仅有7例表现类癌综合征,7例尿中有5-HIAA分泌升高。患者经静脉注射37MBq~(131)I-MIBG后,于24小时、48小时、72小时进行全身闪烁显像检查,注射
~(131)I-MIBG(~(131)I-meta-iodobenzylhydrazine) is an analog of a biogenic amine precursor. In order to evaluate its role in the diagnosis and treatment of carcinoid tumors, the authors used a (131)I-MIBG to visualize 20 patients with carcinoid tumors and treated the patients with the drug. Patients and Methods: 20 cases of carcinoid patients were confirmed by pathology, of which 7 had metastatic lesions and the primary tumor was unknown, only 7 cases showed carcinoid syndrome, and 7 cases had elevated 5-HIAA secretion in the urine. After intravenous injection of 37 MBq 131 I-MIBG, the patient underwent whole body scintigraphy at 24 hours, 48 hours, and 72 hours.