疟疾患者不论由何种疟原虫感染,均有脾肿大为特征。脾肿大在急性感染时可达500克;如果反复发作,还可能倍增。然而,非创伤性或自发性脾破裂尚属罕见。文献上有关间日疟患者自发性脾破裂的报道,只有少数几例,据认为疟疾急性期脾脏迅速肿大,是间日疟时脾破裂的高危因素。本文所报道的致命性脾破裂病例,就作者所知,是在英国第1例由于卵形疟原虫感染所引起。 Regardless of what type of Plasmodium infection, malaria patients are characterized by splenomegaly. Splenomegaly in acute infection up to 500 grams; if repeated attacks may also be doubled. However, non-invasive or spontaneous rupture of the spleen is still rare. In the literature on spontaneous splenic rupture of vivax malaria reported only a few cases, it is thought that acute spleens of malaria swelled rapidly, is the risk of splenic rupture during vivax malaria. The cases of fatal rupture reported here are, as far as the authors know, caused by the first case of Plasmodium ovale infection in the United Kingdom.