论文部分内容阅读
目的:探讨不同检测方法对早产儿胆红素测定的差异,以寻找监测早产儿胆红素动态变化的最佳方法。方法:应用全自动生化分析仪(生化法)、微量胆红素测定仪(微量法)、经皮胆红素检测仪(经皮法)3种测定方法对120例早产儿生后第1天、第3天、第7天的胆红素水平进行动态监测并比较其差异。结果:微量法测定胆红素与生化法结果比较差异无统计学意义(P>0.05);经皮法与生化法比较,胎龄越大,相关性越好(中期早产儿r=0.850,晚期早产儿r=0.904);经过蓝光照射退黄治疗后,微量法和经皮法、经皮法与生化法监测的早产儿胆红素水平比较差异有统计学意义(P<0.05)。结论:微量法动态监测早产儿胆红素结果准确、操作简便,优于生化法和经皮法。
OBJECTIVE: To explore the difference of bilirubin assay in different preterm infants with different test methods in order to find out the best way to monitor the dynamic changes of bilirubin in preterm infants. Methods: The application of automatic biochemical analyzer (biochemical method), trace bilirubin (trace method), percutaneous bilirubin detector (transdermal method) three kinds of determination of 120 cases of premature infants on the first day after birth , 3 days, 7 days of bilirubin levels were dynamically monitored and compared their differences. Results: There was no significant difference between the bilirubin assay and the biochemical assay (P> 0.05). The higher the gestational age, the better the correlation between transdermal and biochemical methods (r = 0.850, r = 0.850 Preterm infant r = 0.904). After treatment with blue light, the level of bilirubin in perinatal and perinatal monitoring of preterm infants was significantly different (P <0.05). Conclusion: The microdialysis method can accurately monitor the bilirubin in preterm infants, and is simple and easy to operate. It is superior to biochemical and transdermal methods.