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[目的]观察大柴胡汤保留灌肠联合奥曲肽治疗水肿型急性胰腺炎疗效。[方法]使用随机平行对照方法,将76例门诊及住院患者按就诊顺序号法简单随机分为两组。维持水电解质平衡、止痛、抗感染治疗。对照组38例奥曲肽,首次0.1mg,静注;后维持50Lg/h速率静滴,0.1mg/次,2h/d,1次/d。治疗组38例大柴胡汤保留灌肠(柴胡20g,黄岑、芍药、大黄各15g,大枣、枳实各12g,玄胡15g,木香10g,丹参15g),1剂/d,水煎100m L,保留灌肠,2h/次;西药治疗同对照组。连续治疗7d为1疗程。观测临床症状、时间指标、不良反应。治疗1疗程,判定疗效。[结果]治疗组痊愈23例,显效7例,有效6例,无效2例,总有效率94.74%。对照组痊愈15例,显效8例,有效5例,无效10例,总有效率73.68%。治疗组疗效优于对照组(P<0.05)。时间指标两组治疗组优于对照组(P<0.01)。[结论]大柴胡汤保留灌肠联合奥曲肽治疗水肿型急性胰腺炎疗效满意,无严重不良反应,值得推广。
[Objective] To observe the therapeutic effect of Dachaihu decoction combined with octreotide on edematous acute pancreatitis. [Methods] Using randomized parallel control method, 76 outpatients and inpatients were randomly divided into two groups according to the sequence number of visiting doctor. Maintain water and electrolyte balance, pain relief, anti-infective treatment. The control group of 38 patients with octreotide, the first 0.1mg, intravenous; maintained at a rate of 50Lg / h infusion, 0.1mg / time, 2h / d, 1 / d. The treatment group 38 cases of Dachaihu decoction retention enema (Bupleurum 20g, Huang Cen, peony, rhubarb each 15g, jujube, citrus aurantium each 12g, Hyun Hu 15g, woody 10g, Salvia 15g), 1 / d, decoction 100m L, retention enema, 2h / times; western medicine treatment with the control group. Continuous treatment 7d for a course of treatment. Observation of clinical symptoms, time indicators, adverse reactions. Treatment of a course of treatment to determine the efficacy. [Results] The treatment group cured 23 cases, markedly effective in 7 cases, effective in 6 cases, ineffective in 2 cases, the total effective rate 94.74%. Control group cured 15 cases, 8 cases markedly effective in 5 cases, 10 cases, the total effective rate was 73.68%. The treatment group was better than the control group (P <0.05). The time index of the two treatment groups was better than that of the control group (P <0.01). [Conclusion] Dazhai Hu decoction combined with octreotide in treating edematous acute pancreatitis has satisfactory curative effect and no serious adverse reactions, which deserves promotion.