输注造影剂可能发生不同的副反应,本文报道1例应用造影剂后在既往创伤部位出现荨麻疹样红斑的同形反应.这种Ⅰ型变态反应表现以往未见报道.患者男性,43岁,曾因二尖瓣反流行心导管术,患者于9年前行尸体肾移植,目前有移植肾肾小球肾炎.一年前因心绞痛应用三碘异酞酰胺行冠状动脉造影,随后行冠状动、静脉移植术,均无并发症,每日服用阿斯匹林、强的松、硫唑嘌呤、地高辛等药物,无变态反应及过敏史.本次采用标准方法使用三碘异酞酰胺50ml进行左室造影,2分钟后病人出现皮肤瘙痒及多部位皮肤反应.在手术及其他瘢痕区、左臂陈旧性动静脉瘘、肘前静脉穿刺及左腿提供静脉移植部位出现瘙痒性苍白丘疹,周围有红斑.临床表现为荨麻疹性红斑,不伴全身症状,无支气管痉挛或低血压发生.经静脉注射氢化可的松100mg及扑尔敏10mg, Infusion contrast agent may have different side effects, this article reports the 1 case of urticaria-like erythema-like homogeneity after the application of contrast agent in the past.It has never been reported in this type of allergy.Patients male, 43 years old, Previously due to mitral valve regurgitation cardiac catheterization, the patient underwent renal transplantation 9 years ago, there are currently renal transplant glomerulonephritis.A year ago due to angina pectoris using triiodoisophthalamide coronary angiography, followed by coronary , Vein graft, no complications, taking daily aspirin, prednisone, azathioprine, digoxin and other drugs, no allergies and allergies this time using the standard method of triiodoisophthalamide 50ml left ventricular angiography, 2 minutes after the patient had skin itching and multi-site skin reaction in the operation and other scar area, the left arm of the old arteriovenous fistula, the antecubital vein puncture and left ventricle vein graft site of itching pale papules , Erythema around the clinical manifestations of urticaria erythema, without systemic symptoms, no bronchospasm or hypotension occurred after intravenous injection of hydrocortisone 100mg and chlorpheniramine 10mg,