不同个体对药物的反应有很大的差异。有少数人对某些药物特别敏感,应用小剂量即可产生毒性反应;而另有少数人对某些药物敏感性极低,应用大剂量甚至中毒量也不产生毒性反应;还有少数人应用某些药物后,出现与群体有质的区别的反应。现有资料证明:药物反应的个体差异主要决定于遗传因素。遗传因素对药物反应的影响,多见于以下两方面: The response of different individuals to drugs varies widely. A few people are particularly sensitive to certain drugs and can produce toxic reactions when using small doses; while others have very low sensitivity to certain drugs and do not produce toxic reactions even with large doses or even toxic doses. There are also a few applications After some drugs, there are qualitative differences with the group reaction. The available data show that: individual differences in drug response depends mainly on genetic factors. Genetic factors on the impact of drug reactions, more common in the following two aspects: