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目的 :探讨输精管及输精管静脉结扎用于预防和治疗良性前列腺增生 (BPH)的可能性及有效率。 方法 :取 5～ 6岁龄雄性杂交犬 4 0只 ,随机分为A、B、C、D 4组 ,每组 10只 ,其中A、B两组喂混合饲料制成BPH模型 ,C、D两组喂普通饲料 ,2年后将A、C两组犬的双侧输精管连同输精管静脉结扎 ,B、D两组犬仅解剖显露输精管 ,但不结扎。继续原方法饲养 2年后将 4 0只犬处死解剖出前列腺称重 ,测量体积 ,然后分组取材制片 ,观察组织学改变。 结果 :A、C两组及B、D两组前列腺重量及体积相比较 ,差异有显著性 (P <0 .0 1)。A、C两组前列腺组织切片呈退行性变而B、D两组呈增生性改变。 结论 :在BPH前行输精管及输精管静脉结扎可减轻犬在老年期的BPH ;在增生后结扎可使犬前列腺组织发生不同程度的萎缩
Objective: To investigate the possibility and efficiency of vasectomy and vas deferens vein ligation in the prevention and treatment of benign prostatic hyperplasia (BPH). Methods: 40 male aged 5 ~ 6 male dogs were randomly divided into A, B, C and D 4 groups, 10 rats in each group, in which A and B groups were fed BPH model, C, D Two groups of normal feed, two years later, A, C dogs bilateral vas deferens with vas deferens ligation, B, D dogs were only anatomically revealed vas deferens, but not ligation. Continue to maintain the original method 2 years after the 40 dogs were sacrificed anatomical prostate weighing, measuring the volume, and then sub-filming production, observed histological changes. Results: There was a significant difference in weight and volume of prostate between groups A and C and groups B and D (P <0.01). A, C two groups of prostate tissue degeneration but B, D two groups showed hyperplastic changes. CONCLUSIONS: Vasectomy and vas deferens vein ligation before BPH can reduce BPH of dogs in the elderly, and ligation of the dogs can cause various degrees of atrophy of the canine prostate tissue after ligation