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一,锰在机体内的蓄积、分布和降解进入机体的锰,在某些器官中相对富集。器官摄锰量,因锰进入的剂量、途径、类型、乃至测定方法等的不同而异。母鼠可经胎盘和乳汁将锰转移到仔鼠体内,后者组织中的锰分布是肝>肾上腺>垂体>肾>大脑、丘脑、睾丸;这种仔鼠如果还接受锰盐灌胃,组织中的锰分布便改变为垂体>丘脑>大脑=肝>肾>肾上腺>睾丸。不同类型的锰化合物,也影响到锰在体内的分布。对小鼠皮下一次和多次重复注射MnCl_2、MMT
First, the accumulation of manganese in the body, distribution and degradation into the body of manganese, relatively enriched in some organs. Organ intake of manganese, due to the amount of manganese into the channels, types, and even the method of measurement varies. The maternal mouse can transfer manganese to the offspring through the placenta and milk, and the distribution of manganese in the latter tissue is liver> adrenal gland> pituitary gland> kidney> brain, thalamus and testis; if the offspring also receive manganese salt gavage, In the distribution of manganese will change to the pituitary> thalamus> brain = liver> kidney> adrenal> testis. Different types of manganese compounds also affect the distribution of manganese in the body. Mice were injected subcutaneously once and repeatedly with MnCl 2, MMT