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目的超声弹性成像联合血清CA153检测在乳腺癌诊断中的临床意义。方法选择乳腺癌患者80例、乳腺良性肿块患者60例,术前行超声弹性成像检查进行评分,采用免疫放射分析法(试剂盒由北京原子能研究院同位素研究所提供)检测血清CA153含量。结果乳腺癌组CA153、UE评分均高于乳腺良性肿瘤组,差异有统计学意义(P<0.01)。2项联合检测的敏感性和诊断准确率均比单项检测高。结论超声弹性成像联合血清CA153检测对可以明显提高乳腺癌患者诊断的准确性及敏感性。
Objective To evaluate the clinical significance of ultrasound elastography combined with serum CA153 in the diagnosis of breast cancer. Methods Eighty patients with breast cancer and 60 patients with benign breast mass were selected and scored by ultrasound elastography preoperatively. Serum CA153 levels were determined by immuno-radio-immunoassay (kit provided by Institute of Isotopes, Beijing Institute of Atomic Energy). Results The scores of CA153 and UE in breast cancer group were significantly higher than those in benign breast tumor group (P <0.01). The sensitivity and diagnostic accuracy of the two combined tests were higher than the single test. Conclusion Ultrasound elastography combined with serum CA153 detection can significantly improve the diagnostic accuracy and sensitivity of patients with breast cancer.