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目的探讨呼吸内科应用抗菌药物干预的临床效果。方法选取本院2013年1～3月的179例患者作为干预组,2013年1月前出院的179作为对照组。采用本院制定的干预方式进行合理干预,比较干预组与对照组两组患者抗菌药使用率,抗菌药物费用占总费用的比例,不合理给药情况,患者的住院时间。结果与对照组相比,患者抗菌药物的使用率从85.03%下降至70.57%(P<0.05);患者平均每人的抗菌药物费用支出比例从干预前60.13%降至干预后的44.79%(P<0.05),干预效果明显。平均住院天数有一定程度的下降,从干预前的(19.03±5.34)d降至干预后的(10.11±3.43)d,明显缩短患者的住院天数(P<0.05)。不合理用药情况亦得到明显改善,从干预前20.21%下降到7.01%。结论对本院呼吸内科应用抗菌药物实行合理的干预能够明显的改善疗效,减轻患者经济负担,节约医疗资源,值得临床应用推广。
Objective To investigate the clinical effects of antimicrobial intervention in respiratory medicine. Methods 179 patients from January to March 2013 in our hospital were selected as the intervention group and 179 patients discharged before January 2013 as the control group. Interventions made by our hospital were used to make reasonable interventions. The usage of antimicrobials, the proportion of antimicrobials to total costs, unreasonable dosage and patient’s hospital stay were compared between intervention group and control group. Results Compared with the control group, the rate of antimicrobial use decreased from 85.03% to 70.57% (P <0.05). The average cost per patient for antimicrobial drugs decreased from 60.13% before intervention to 44.79% after intervention (P <0.05), the intervention effect is obvious. The mean length of hospital stay decreased to some extent from 19.03 ± 5.34 days before intervention to 10.11 ± 3.43 days after intervention, which significantly shortened the hospitalization days (P <0.05). Unreasonable drug use has also been significantly improved from 20.21% before intervention to 7.01%. Conclusion The rational intervention of antimicrobial agents in respiratory medicine can significantly improve the curative effect, reduce the financial burden on patients and save medical resources, which is worthy of clinical application.