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家兔静脉注射丹参(2g/kg)后,左肾缺血60min再灌流30min,其皮质内过氧化脂质(LPO)含量比注药前自身右肾的含量下降26.68％。丹参组缺血—再灌流肾LPO含量下降的幅度也显著大于葡萄糖组、提示丹参可能具有较强的抗氧化作用,对防治肾缺血—再灌流损害具有积极意义。
After rabbits were intravenously injected with salvia miltiorrhiza (2g/kg), the content of peroxidized lipid (LPO) in the cortex was decreased by 26.68% compared with the right kidney before injection. The decrease of LPO content in the ischemic-reperfused kidney of the Salvia miltiorrhiza group was also significantly greater than that of the glucose group, suggesting that the Salvia miltiorrhiza may have a strong anti-oxidation effect, which is of positive significance for prevention and treatment of renal ischemia-reperfusion injury.