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摘要目的探讨扩散峰度成像(DKI)用于评估局灶性进展期直肠癌病人新辅助放化疗治疗反应的可行性及其价值。方法纳入41例病人。所有病人在新辅助放化疗前后均行3 T MRI动态增强检查。测量影像指标(Dapp、Kapp和AD值)。计算变化值(ΔX)和变化率(rΔX)。病理上肿瘤消退分级评分(Mandard)为参考标准(反应良好:pTRG 1~2;反应不良:pTRG 3~5)。使用ROC分析比较诊断性能。结果在新辅助放
Abstract Objective To investigate the feasibility and value of diffusion kurtosis imaging (DKI) in evaluating neoadjuvant chemoradiation response in patients with focal rectal cancer. Methods included 41 patients. All patients underwent 3 T MRI dynamic contrast enhancement before and after neoadjuvant chemoradiation. Measure the image indicators (Dapp, Kapp and AD values). The change value (ΔX) and the change rate (rΔX) were calculated. Pathological tumor regression score (Mandard) as a reference standard (good response: pTRG 1 ~ 2; poor response: pTRG 3 ~ 5). Use ROC analysis to compare diagnostic performance. Results in the new auxiliary release