Antifertility effects of methanolic pod extract of Albizzia lebbeck (L.) Benth in male rats

来源 :Asian Journal of Andrology | 被引量 : 0次 | 上传用户:flyfox521
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Aim: To evaluate the antifertility activity of the methanolic pod extract of Albizzia lebbeck (L.) Benth in male albino rats. Methods: The methanolic pod extract of Albizzia lebbeck was administrated orally for 60 days at 50, 100 and 200 mg·kg-1·day-1 to male albino rats. Sperm motility and density in cauda epididymides were assessed. Biochemical and histological analysis were performed in blood samples and reproductive organs. Results: A. lebbeck pod extract brought about a significant decrease in the weights of testis, seminal vesicles, epdidymis and ventral prostate. The sperm motility and density were significantly reduced. There was a marked reduction in the numbers of primary spermatocytes, secondary spermatocytes and spermatids. The Sertoli cell count as well as its cross sectional surface area were significantly decreased. The Leydig cell nuclear area and the number of mature Leydig celis were also significantly decreased. The protein, glycogen and cholesterol content of the testis, the fructos Method: The methanolic pod extract of Albizzia lebbeck was administrated orally for 60 days at 50, 100 and 200 mg·kg- 1. day-1 to male albino rats. Sperm motility and density in cauda epididymides were assessed. Biochemical and histological analysis were performed in blood samples and reproductive organs. Results: A. lebbeck pod extract brought about a significant decrease in the weights of testis The Sertoli cell count as well as its cross sectional surface area was significantly reduced, that is to say, the sperm motility and the density of the sperm were decreased. There was a marked reduction in the numbers of primary spermatocytes, secondary spermatocytes and spermatids. The Leydig cell nuclear area and the number of mature Leydig celis were also significantly decreased. The protein, glycogen and cholesterol content of the Testis, the fructos
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