患儿男，12岁，因走路跌伤后右眼痛，视力下降3天就医。该患儿出生后17个月始会走路，近2岁出门牙2个，7岁时会说成句话，吐字欠清晰。患儿足月顺产；第2胎。生后曾短暂窒息，无高烧，无袖风史，无外伤史。其父、母亲否认近亲婚配。其母患有甲亢，妊娠期无患病及用药史，有姐姐 Children male, 12 years old, right eye pain due to walking injury, vision loss for 3 days for medical treatment. The child will be walking 17 months after birth, nearly 2 years out of 2 teeth, 7 years old will be said to be sentence, articulation is not clear. Children with full-term follow-up; the second child. A short asphyxia after birth, no high fever, no sleeve wind history, no history of trauma. His father and mother denied that their relatives were married. The mother suffering from hyperthyroidism, no history of pregnancy and medication history, a sister