论文部分内容阅读
为了探讨冷刀宫颈锥切术对宫颈上皮内瘤变的诊断治疗作用,并评价临床疗效,回顾性分析因宫颈病变行宫颈细胞学检查、阴道镜下多点活检和宫颈锥切术的患者186例,对比宫颈锥切术和阴道镜下多点活检的病理检查结果,分析冷刀宫颈锥切术的临床疗效和并发症。两者病理完全符合138例,占74.2%,不符合48例,占25.8%。8例(4.3%)患者锥切边缘受累,治愈率为98.9%,复发率为1.1%。发现早期浸润癌5例,其中2例仅行宫颈锥切随访无复发。11例患者后行子宫切除术或扩大子宫切除术。冷刀宫颈锥切术的主要并发症为出血和宫颈管狭窄,发生率分别为4.3%(8/186)和1.6%(3/186)。初步研究结果提示,宫颈锥切术比阴道镜下多点活检对宫颈上皮内瘤变的诊断更准确,并具有重要治疗作用。
In order to explore the diagnosis and treatment of cervical intraepithelial neoplasia by cold knife cervical conization, and to evaluate the clinical effect, retrospective analysis of patients with cervical cytology due to cervical lesions, colposcopy multipoint biopsy and cervical conization Cases, contrast cervical conization and colposcopy biopsy results of pathological examination, cold knife cervical conization clinical efficacy and complications. Pathology of the two completely consistent with 138 cases, accounting for 74.2%, does not conform to 48 cases, accounting for 25.8%. In 8 cases (4.3%) patients had conus margins, the cure rate was 98.9% and the recurrence rate was 1.1%. Early invasive carcinoma was found in 5 cases, of which 2 cases were followed up only cervical conization without recurrence. Eleven patients underwent hysterectomy or extended hysterectomy. The main complications of cold knife cervical conization were bleeding and cervical stenosis, with rates of 4.3% (8/186) and 1.6% (3/186), respectively. Preliminary findings suggest that cervical conization is more accurate than colposcopy biopsy for the diagnosis of cervical intraepithelial neoplasia and has an important therapeutic effect.