1研究背景颈动脉粥样硬化易损斑块破裂引发的血栓栓塞,是缺血性卒中的主要致病原因之一。关于中国卒中患者颈动脉严重狭窄(狭窄>50%)的发生率报道不一(13%~41.7%),而更多学者认为颅内动脉病变是中国人群发生缺血性卒中的主要原因。准确识别颈动脉易损斑块并研究其人群分布特征对卒中的防控具有重要意义。过去绝大多数研究均采用血管成像技术来测量动脉管腔的狭窄程度,以此来评估斑块的易损 1 Background Carotid artery atherosclerosis vulnerable plaque rupture caused by thromboembolism, is one of the main causes of ischemic stroke. The prevalence of severe carotid stenosis (> 50%) in Chinese stroke patients varies widely (13% -41.7%). More and more scholars think intracranial arterial disease is the main cause of ischemic stroke in Chinese population. Accurate identification of carotid vulnerable plaque and study of its population distribution characteristics of stroke prevention and control is of great significance. In the past, most studies used angiography to measure the degree of stenosis in the arterial lumen in order to assess the vulnerability of the plaque