我国在用光镜研究食管上皮增生与癌变等方面取得可喜成绩,并证明重度增生病人癌发生率26.6％,比正常组(0.19％)高140倍。提出正常食管上皮细胞是由轻度增生经重度增生而发展为癌。说明正常、增生到癌变三者之间有着紧密联系。从超结构水平上研究这一癌变过程是一项非常重要的工作,迄今在国内外文献中均未见报导,我 China has made gratifying achievements in the use of light microscopy to study esophageal epithelial hyperplasia and canceration, and has demonstrated that the incidence of cancer in patients with severe hyperplasia is 26.6%, which is 140 times higher than that in the normal group (0.19%). It is proposed that normal esophageal epithelial cells develop from a mild hyperplasia to a severely hyperplastic carcinoma. It shows that there is a close relationship between normal and hyperplasia to cancer. The study of this carcinogenesis process at a superstructure level is a very important task and has not been reported so far in domestic and foreign literature.