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浅表性肿瘤或其癌前病变的局部免疫治疗法,近十年来进展较快。本疗法不仅对皮肤原发性肿瘤包括棘手的皮肤癌综合症等有一定疗效,对转移性病灶也有姑息疗效。其方法是在肿瘤中或瘤旁应用一定量的某种免疫原(抗原),引致局部迟发性超敏性激惹反应(Delayed hypersensitivity challenge reactlon下称激惹反应),这个反应有选择性抗瘤作用,即对肿瘤组织有破坏、消散作用,而对正常组织不起反应,或反应较小易于恢复。
Local immunotherapy for superficial tumors or their precancerous lesions has progressed rapidly in the past decade. This therapy not only has a certain effect on primary skin tumors, including intractable skin cancer syndromes, but also has a palliative effect on metastatic lesions. The method is to apply a certain amount of an immunogen (antigen) in the tumor or beside the tumor, causing a local delayed hypersensitivity challenge reacton, which is selective response. The role of the tumor, that is, the destruction of tumor tissue, the role of dissipating, but can not respond to normal tissue, or less easily recovered.