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目的:探讨在HPV16(+)与其他高危型HPV(+)时电子阴道镜诊断不同级别宫颈病变的差异。方法:对94例可疑宫颈细胞学(TCT)异常的维吾尔族妇女行电子阴道镜检查,检查前采用核酸分子快速导流杂交基因分型技术进行HPV分型检测并行阴道镜下多点活检,比较在HPV16(+)与高危非HPV16(+)两组中电子阴道镜诊断不同级别宫颈病变的检出率。结果:电子阴道镜辨认HPV16(+)中的CINⅡ病变超过高危非HPV16(+)(P<0.05)。其中电子阴道镜诊断HPV16(+)的CINⅡ敏感性高于高危非HPV16(+)(P<0.01)。结论:电子阴道镜诊断HPV16(+)的CINⅡ及以上级别病变的敏感性高于高危非HPV16(+)。
Objective: To explore the difference between different levels of cervical lesions detected by electronic colposcopy in HPV16 (+) and other high-risk HPV (+). Methods: Ninety - four Uygur women with suspected cervical cytology (TCT) abnormalities were examined by electronic colposcopy. Before the examination, rapid genotyping of nucleic acid was used to detect the HPV type. Multiple colposcopy biopsies were performed. In the HPV16 (+) and high-risk non-HPV16 (+) two groups of electronic colposcopy in the diagnosis of different levels of cervical lesions detection rate. Results: Electron colposcopy identified HPV16 (+) CINII lesions over high-risk non-HPV16 (+) (P <0.05). Among them, CIN II sensitivity of HPV16 (+) detected by electronic colposcopy was higher than that of high-risk non-HPV16 (+) (P <0.01). Conclusion: The sensitivity of electronic colposcopy in diagnosing CIN Ⅱ and above lesions of HPV16 (+) is higher than that of high-risk non-HPV16 (+).