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目的探讨结直肠癌患者淋巴结转移状态与预后和病理参数之间的关系。方法回顾性分析87例结直肠癌根治性切除患者的临床资料。结果 87例患者检出淋巴结共计866个;其中,转移淋巴结共计130个,总体淋巴结转移率(LNR)为15.0%。有淋巴结转移者3年生存率为62.2%,低于无淋巴结转移者的88.0%(P<0.05)。淋巴结转移个数为1-3个者3年生存率为73.1%,高于超过3个者的36.4%(P<0.05)。LNR为1%-15%患者的3年生存率为83.3%,高于LNR 16%-40%的70.6%和LNR>40%的42.9%(P<0.05)。结论 LNR与结直肠癌患者的预后密切相关,可作为简单、有效的评估预后指标。
Objective To investigate the relationship between lymph node metastasis and prognosis and pathological parameters in patients with colorectal cancer. Methods The clinical data of 87 patients with radical resection of colorectal cancer were retrospectively analyzed. Results A total of 866 lymph nodes were detected in 87 patients. Among them, there were 130 metastatic lymph nodes with a total lymph node metastasis rate (LNR) of 15.0%. The 3-year survival rate with lymph node metastasis was 62.2%, which was lower than 88.0% without lymph node metastasis (P <0.05). The 3-year survival rate of lymph node metastasis was 73.1%, which was higher than 36.4% of those with more than 3 (P <0.05). The 3-year survival rate was 83.3% for those with LNR of 1% -15%, higher than 70.6% for LNR 16% -40% and 42.9% for LNR> 40% (P <0.05). Conclusions LNR is closely related to the prognosis of patients with colorectal cancer and can be used as a simple and effective prognostic indicator.