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采用回顾性定群研究方法,对济南市119例输血后丙型肝炎感染情况进行了调查。结果表明,119例受血者中,抗-HCV阳性31例,阳性率为26.1%,其中14例为临床丙型肝炎患者,罹患率为11.7%。输入经筛检血液的受血者中,HCV感染率和丙肝罹患率分别为14.6%和4.2%,输入未经筛检血液者分别为33.8%和16.9%,差异有显著性(P<0.05,RR=2.30RR=4.02)。对输血量,输血次数及住院天数双向筛选法多元线性逐步回归分析表明,输血量是影响受血者感染HCV的主要因素。
A retrospective population-based study was conducted to investigate the status of hepatitis C infection in 119 cases of transfusion in Jinan City. The results showed that of the 119 recipients, 31 were positive for anti-HCV, the positive rate was 26.1%. Among them, 14 were clinical hepatitis C patients with an attack rate of 11.7%. In the blood recipients who were screened for blood, the prevalence of HCV infection and hepatitis C were 14.6% and 4.2%, respectively, with 33.8% and 16.9% of the untreated blood, respectively There was significant (P <0.05, RR = 2.30RR = 4.02). The multiple linear stepwise regression analysis of blood transfusion, number of transfusions and length of hospital stay showed that transfusion volume was the main factor influencing HCV infection in recipients.