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[Objective] To research the protective effects of Lycium ruthenicum Murr on irradiated mice. [Methods] Except normal control group,mice were radiated by X-Rays with the radiation dosage being 5 Gy. The RBC,WBC,PLT and HGB of mice were detected. The thymus and spleen indices were calculated. The antioxidase activity,DNA,caspase-3 and caspase-6 contents were detected. [Results] L. ruthenicum water extracts significantly enhanced the hemogram of irradiated mice,increased the SOD activity,improved DNA content,reduced the CAT,GSH-PX and T-AOC activities,and lowered the caspase-3 and caspase-6 contents. Viscera index showed no statistical significance.[Conclusions]L. ruthenicum water extracts had certain protective effects on irradiated mice.
[Methods] To research the protective effects of Lycium ruthenicum Murr on irradiated mice. [Methods] Except normal control group, mice were radiated by X-Rays with the radiation dosage being 5 Gy. The RBC, WBC, PLT and HGB of mice were The effects of DNA, caspase-3 and caspase-6 contents were detected. [Results] L. ruthenicum water extracts significantly enhanced the hemogram of irradiated mice, increased the SOD activity, improved DNA content, reduced the CAT, GSH-PX and T-AOC activities, and lowered the caspase-3 and caspase-6 contents. [Conclusions] L. ruthenicum water extracts had certain protective effects on irradiated mice.