肠病相关T细胞淋巴瘤(EATL)来源于小肠上皮细胞,人群发病率低,恶性程度大,疾病进展快,预后极差,中位生存期大约7.5个月。患者临床症状不典型,误诊率高,且通常一般状态差,对治疗耐受性差,暂时缺乏标准的治疗方案。本文报道一例EATL。女性,43岁,2012年1月起出现腹部隐痛,于当地医院口服头孢克洛抗感染治疗后无明显好转,且病情逐渐加重,出现乏力、盗汗等不适症状。2012年2月21日下午突发腹痛,以中下腹为主,疼痛剧烈,呈持续性,伴恶心、呕吐,发热、寒战,最高体温 Enteropathy-associated T-cell lymphoma (EATL) is derived from small intestine epithelial cells and has a low incidence, a high degree of malignancy, rapid disease progression, and a very poor prognosis with a median survival of approximately 7.5 months. Patients with atypical clinical symptoms, high misdiagnosis, and usually poor general condition, poor tolerance to treatment, the temporary lack of standard treatment. This article reports an example of EATL. Female, age 43, developed abdominal pain from January 2012 and no significant improvement after oral administration of cefaclor anti-infective in a local hospital. The condition gradually aggravated and symptoms such as fatigue and night sweats appeared. On the afternoon of February 21, 2012, sudden abdominal pain occurred mainly in the middle and lower abdomen. The pain was severe and persistent with nausea, vomiting, fever, chills, and maximum body temperature