牙周膜相关蛋白(PLAP)-1为新确定的小分子富亮氨酸蛋白聚糖家族中的成员,是一种新的负性调节牙周膜矿化的因子,在牙周组织中特异性表达,在牙周组织动态平衡的自身稳定中起关键的作用。下面就PLAP-1的结构、组织分布和功能特点以及在牙周膜中的作用与调控机制等研究进展作一综述。 Periodontal ligament associated protein (PLAP) -1 is a newly identified small molecule rich leucine family members, is a new negative regulation of periodontal membrane mineralization factor in the periodontal tissue specific Sexual expression plays a pivotal role in the self-stability of periodontal tissue homeostasis. The following is a summary of the research progress of PLAP-1 structure, tissue distribution and functional characteristics, and its role in the periodontal ligament and its regulatory mechanisms.