本研究用食蟹猴疟原虫—猴模型进行。初步结果表明,引自越南的食蟹猴疟原虫对氯喹可产生适应性,它较易于子孢子感染后经诱导而产生。适应性表现为受感染猴原虫再现时,再给服氯喹,随后原虫转阴,但在短间隔期内又见原虫再现。已对氯喹产生了适应性的食蟹猴疟原虫,血传转种给另外的健康猴,排除了红外期引起的复发,原虫再现的现象继续发生。适应氯喹而引起的原虫再现易误认为都是红外期引起的复发。 This study was conducted with a C. macaque-monkey model. The preliminary results show that Plasmodium cynocerus from Vietnam can be adapted to chloroquine, which is more easily induced by sporozoite infection. Adaptation of the performance of infected monkey protozoan reappearance, and then served to chloroquine, followed by protozoa turned negative, but in the short interval see protozoan reproduction. Chloroquine has been adapted to produce cercopithecus macaque, blood transfusions to other healthy monkeys, ruled out the recurrence caused by infrared, protozoan reproduction continued to occur. Acclimate to chloroquine caused protozoa reproduction easily mistaken for both are caused by the recurrence of the infrared.