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目的为了使基层医师更简单了解慢性化脓性胫骨骨髓炎窦道分泌物致基层医生病菌的组成，从而合理使用抗生素。方法对80例已经明确培养出致病菌并完成药敏结果的样本进行统计分析。结果80例标本共培养出120株病原菌；有2种或2种以上的致病菌占标本例数的55%，混合感染较严重。结论参考致病菌组成及药敏特点，提出临床合理化建议。“,”Objective It is to guide basic-level doctors how to use antibacterial drugs by clearly understanding the composition of pathogenic bacteria in chronic suppurative tibia osteomyelitis.Methods Statistical analysis is used to 80 cases which have got en pathogenic bacteria and drug sensitivity results.Results 120 strains of pathogenic bacteria are got en from these 80 cases,the ratio of cases with 2 and more than 2 kinds of pathogenic bacteria is 55%,so mixed infection is serious.Conclusion Rational suggestions are proposed based on composition of pathogenic bacteria and characteristics of drug sensitivity.