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强的松龙伴用或不伴用硫唑嘌呤的疗法已广泛用于治疗慢性活动性肝炎(慢活肝),它对HBsAg阴性患者,尤其是对“自身免疫”性肝炎有效。但常规剂量的强的松龙对HBsAg阳性慢活肝无效。近年来许多资料指出这种疗法可增加病毒的复制,并可导致病情恶化。本文观察在HBeAg阳性或抗-HBe阳性的慢性乙型肝炎病人中开始或终止强的松龙/硫唑嘌呤的治疗对病毒复制标志(HBs-Ag、HBeAg、抗-HBe和DNAP)及肝功能生化试验的变化,从而确定这种疗法对哪一
Prednisolone with or without azathioprine has been widely used to treat chronic active hepatitis (slow-living liver) and is effective in HBsAg-negative patients, especially for “autoimmune” hepatitis. However, the conventional dose of prednisolone HBsAg-positive chronic liver failure. In recent years, many sources point out that this therapy can increase the replication of the virus and lead to the progression of the disease. This article investigates the effect of treatment with prednisolone / azathioprine on viral replication markers (HBs-Ag, HBeAg, anti-HBe and DNAP) and liver function in HBeAg-positive or anti-HBe positive chronic hepatitis B patients Changes in biochemical tests to determine which of this therapy