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目的探讨阿奇霉素在儿科临床使用过程中的不良反应极其药学观察。方法对来医院诊治的80例患儿入院资料进行分析,将其随机分为试验组和对照组各40例。对照组注射阿曲霉素治疗,试验组口服阿曲霉素,比较2组不良反应及其临床药学特点。结果试验组不良反应率为25.0%,低于对照组的不良反应率35.0%,差异有统计学意义(P<0.05)。结论阿奇霉素在儿科临床应用中不良反应发病率较高,患儿用药时应该根据患儿临床症状等综合用药,尽可能口服用药,降低患儿用药过程中的不良反应。
Objective To investigate the side effects of azithromycin in pediatric clinical use. Methods The hospital admission data of 80 cases diagnosed and treated by the hospital were analyzed and randomly divided into experimental group and control group of 40 cases. The control group was treated with azithromycin, and the test group was orally administered with monascus. The adverse reactions and the clinical pharmacy characteristics of the two groups were compared. Results The rate of adverse reactions in the experimental group was 25.0%, which was lower than that in the control group (35.0%), the difference was statistically significant (P <0.05). Conclusion Azithromycin has a high incidence of adverse reactions in pediatric clinical application. When taking drugs, the children should be treated according to the clinical symptoms of the children and treated with oral medication as much as possible to reduce the adverse reactions during the medication.