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目的评价血凝酶联合兰索拉唑治疗上消化道出血的疗效及其安全性。方法选取上消化道出血病人111例,随机分为治疗组58例和对照组53例。在积极补液、输血等措施基础上,对照组单纯予兰索拉唑60mg/d静脉滴注;治疗组在对照组治疗基础上加用血凝酶1000U静脉注射,2次/d,共3d。分别观察2组止血效果、显效率、总有效率及不良反应。结果治疗组总有效率96.6%,对照组总有效率为90.6%,2组差异无统计学意义(P>0.05);治疗组显效率(44.8%)高于对照组(22.6%),差异有统计学意义(P<0.05)。2组用药均无明显不良反应。结论血凝酶联合兰索拉唑治疗上消化道出血安全有效,显效率高。
Objective To evaluate the efficacy and safety of hemagglutinin combined with lansoprazole in the treatment of upper gastrointestinal bleeding. Methods 111 cases of upper gastrointestinal bleeding were randomly divided into treatment group (58 cases) and control group (53 cases). On the basis of positive rehydration, blood transfusion and other measures, the control group was treated with lansoprazole 60 mg / d intravenously alone. The treatment group was given intravenous injection of hemagglutinin 1000U twice a day for 3 days on the basis of the control group. Two groups were observed hemostatic effect, markedly effective rate, the total effective rate and adverse reactions. Results The total effective rate was 96.6% in the treatment group and 90.6% in the control group, with no significant difference between the two groups (P> 0.05). The effective rate (44.8%) in the treatment group was significantly higher than that in the control group (22.6% Statistical significance (P <0.05). No adverse reactions were found in the two groups. Conclusion Hemagglutinin combined with lansoprazole in the treatment of upper gastrointestinal bleeding is safe and effective, with high efficiency.