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以 2 苯基 4 甲酰基 1,2 ,3 三唑为原料和芳胺缩合生成一系列Schiff碱 3 .Schiff碱 3与氯乙酰氯或苯氧乙酰氯在三乙胺条件下发生 [2 +2 ]环加成得到单环 β 内酰胺衍生物 4a～ 4f或 5a～ 5f .噻唑啉酮衍生物 6是由Schiff碱 3与巯基乙酸缩环得到 .化合物 4a～ 4f,5a～ 5f和 6a～ 6f的组成及结构经元素分析 ,IR ,1HNMR和MS确证 .
A series of Schiff base 3 was synthesized by the condensation of 2-phenyl-4-formyl-1,2-triazole with aromatic amines. Schiff base 3 reacted with chloroacetyl chloride or phenoxyacetyl chloride in the presence of triethylamine [2 + 2 ] To obtain the monobactinolactam derivatives 4a to 4f or 5a to 5f. The thiazolone derivative 6 is obtained by condensation of Schiff base 3 with thioglycolic acid The compounds 4a to 4f, 5a to 5f and 6a to 6f The composition and structure were confirmed by elemental analysis, IR, 1HNMR and MS.