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不明原因发热(Fuo)是目前诊断中的一个难题。大多数Fuo是由感染性疾病、血管胶原性疾病及肿瘤等引起,发达国家以后两类疾病常见,在发展中国家感染性疾病仍是Fuo最常见的原因。 不论是感染性疾病或肿瘤,肝脏及胆道常是引起Fuo的隐匿病变场所。在研究Fuo病人时检测血清AKP对诊断常有很大帮助。结合体温升高及AKP水平的增加提示播散性结核病、淋巴瘤、原发或转移肝脏肿瘤的可能。血清转氨酶在这些病例中多数变化轻微或正常。
Unexplained fever (Fuo) is currently a diagnosis of a problem. Most Fuo is caused by infectious diseases, vascular collagen diseases and tumors. Two types of diseases are common in developed countries. Infectious diseases in developing countries are still the most common cause of Fuo. Whether it is an infectious disease or tumor, the liver and the biliary tract often cause Fuo’s hidden lesions. Measuring serum AKP when studying Fuo patients is often of great help in the diagnosis. Combination of elevated body temperature and increased AKP levels suggest that disseminated tuberculosis, lymphoma, primary or metastatic liver tumors may be. Serum aminotransferases are mostly mild or normal in these cases.