早在1947年Sawyer等报告,α-肾上腺素能阻断剂双苄胺能抑制兔的诱发排卵,脑室注入去甲肾上腺素(NE)则可诱发排卵。提示中枢神经介质在调节垂体促性腺激素(GTH)的分泌中可能有重要作用。以后,特别是近十年来,大量资料都支持这一见解。虽然大部分研究是关于黄体生成素(LH)的,卵泡刺激素(FSH)的 As early as 1947, Sawyer et al reported that bis-benzylamine, an α-adrenergic blocker, inhibited ovulation induction in rabbits and intrantricular injection of norepinephrine (NE) induced ovulation. It is suggested that central nervous system may play an important role in regulating the secretion of gonadotropin (GTH). Later, especially in the last decade, a great deal of information supports this view. Although most of the research is about luteinizing hormone (LH), follicle stimulating hormone (FSH)