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奥美拉唑(Omeprazole,OME),是一种新型的胃酸分泌抑制剂。该药1979年由瑞典Astra 制药公司合成,1982年首次应用于临床,由于对消化性溃疡的疗效显著而得到临床上的重视。现就OME 的药理作用和临床应用作一综述。
Omeprazole (OME), a novel gastric acid secretion inhibitor. The medicine was synthesized by Swedish Astra Pharmaceutical Company in 1979 and was first applied to clinic in 1982, which has been clinically valued due to the remarkable curative effect on peptic ulcer. Now on the pharmacological effects of OME and clinical application are reviewed.