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肠道代谢产物氧化三甲胺与心血管病的关系在近年来受到研究人员的重视。氧化三甲胺促进动脉粥样硬化的发生发展，血浆氧化三甲胺水平在缺血性心脏病、心力衰竭患者中明显升高，对心血管病患者发生不良事件有预测价值。现就当前对氧化三甲胺与心血管病关系的相关研究进行综述。“,”Trimethylamine N-oxide (TMAO),which is derived from gut microbiota metabolites of specific dietary nutrients ,has e-merged a key contributor in the development of cardiovascular disease in recent years .It has been shown that TMAO promotes atherosclerotic lesion development and progression .It is reported that elevated TMAO levels are reported to be strongly linked to the poor outcomes in pa -tients with ischemic heart disease and heart failure .This article is to reviews the current understanding regarding the role of TMAO in the car -diovascular disease .