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目的:探讨2型糖尿病患者体脂与血糖、C肽之间的相关性。方法:选取我院2型糖尿病患者共65例。测定腰臀比、体脂肪含量、体重指数、体脂肪率及腰围,并采用标准馒头试验与精氨酸刺激试验测定C肽、血糖。结果:腰臀比、体脂肪含量、体重指数、体脂肪率及腰围,与空腹血糖值、餐后2h血糖、HbA1c之间无显著性相关性(P>0.05);腰臀比与0、3、5minC肽呈现为正相关(P<0.05);腰围与1、2h及0、5minC肽呈现为正相关(P<0.05);体重指数与1、2h及0、5minC肽呈现为正相关(P<0.05);体脂肪含量与1、2h及0、3、5minC肽呈现为正相关(P<0.05)。结论:2型糖尿病患者的体脂增多及其分布异常,均会加重胰岛B细胞的负担,导致患者出现胰岛素抵抗症状。
Objective: To investigate the correlation between body fat and blood sugar and C-peptide in type 2 diabetic patients. Methods: A total of 65 patients with type 2 diabetes in our hospital were selected. The waist-to-hip ratio, body fat content, body mass index, body fat percentage and waist circumference were measured. C-peptide and blood sugar were measured by standard bread test and arginine stimulation test. Results: There was no significant correlation between waist-hip ratio, body fat percentage, body mass index, body fat percentage and waist circumference, fasting blood glucose level, postprandial 2h blood glucose and HbA1c (P> 0.05) (P <0.05). There was a positive correlation between waist circumference and 1,2 and 0,5min peptide (P <0.05), while body mass index was positively correlated with 1,2 and 0,5min peptide <0.05). Body fat content showed a positive correlation with 1,2h and 0,3,5min peptide (P <0.05). Conclusion: The increase of body fat and its abnormal distribution in patients with type 2 diabetes will exacerbate the burden of pancreatic islet B cells, resulting in insulin resistance in patients with symptoms.