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自氯丙嗪应用于精神科临床以来,至今已合成了不少抗精神病药;临床实践证明,这些药物具有特异的抗精神病作用,也常伴有锥体外系副作用。通过廿多年来对大脑结构、生理、生化、药理等研究,发现脑内存在着某些对保持和调节正常精神活动起着重要作用的化学物质,即中枢神经递质等,并认为精神病的生化机制与脑内某些化学物质
Since chlorpromazine has been used in psychiatric clinics, many antipsychotic drugs have been synthesized so far. Clinical practice has proved that these drugs have specific antipsychotic effects and are often accompanied by extrapyramidal side effects. After more than 20 years of brain structure, physiology, biochemistry, pharmacology and other studies, found that the brain there are some to maintain and regulate normal mental activity plays an important role in the chemical substances, that is, the central nervous system neurotransmitters, and that the psychosis of biochemistry Mechanisms and certain chemicals in the brain