川畸氏病(Kawasaki病)又称皮肤粘膜淋巴结综合征(Mucocutaneous Lymphnade Syndrome,MC-LS),是原因不明的发热、出疹性疾病,其临床表现是以发热、眼结膜充血、淋巴结肿大、皮肤出疹为特征。1962年首先由日本医生川畸氏(Tomisaku Kaw-asaki)描述。近年来我国东北、成都、南京、上海等地都有报导,广州地区尚未见报告。我院在1982年12月至1983年共收治三例,现报告如下。例1 男,4个月,住院号223977。因发热、咳嗽3天,气促,皮肤潮红1天,以支气管肺炎住院。体温39.5℃,呼吸40次,脉搏140次。皮肤潮红,咽红,心律整,无杂音,两肺可闻干啰音,肝大肋下2.5cm,脾未扪及。实验室检查:周围血白细胞总数15700,带状核3％,分叶核77％,淋巴细胞20％,红细胞300万,血红蛋白9.2g,血小板19万,抗“O”1/333阴性。血沉110mm/小时,血清蛋白电泳:A53％,α_15.1％,α_221％,β12.2％,γ8.8％。X线胸片示支气管炎。心电图见窦性心动过速。入院即用庆大霉素、红霉素、 Kawasaki disease (Mucocutaneous Lymphnade Syndrome, MC-LS), is an unexplained fever, rash disease, its clinical manifestations are fever, conjunctival congestion, swollen lymph nodes , Skin rash is characterized. First described by Japanese doctor Tomisaku Kaw-asaki in 1962. In recent years, northeast China, Chengdu, Nanjing, Shanghai and other places have reported that no reports have been made in Guangzhou. Our hospital in December 1982 to 1983 were treated in three cases, are as follows. Example 1 male, 4 months, hospital number 223977. Due to fever, cough for 3 days, shortness of breath, skin flushing 1 day, hospitalized with bronchial pneumonia. Temperature 39.5 ℃, breath 40 times, pulse 140 times. Skin flushing, throat, heart rhythm, no noise, lungs can be heard dry rales, liver ribs 2.5cm, the spleen is not palpable. Laboratory tests: the total number of peripheral blood leukocytes 15700, 3% ribbons, leaf nuclei 77%, lymphocytes 20%, erythrocytes 3000000, hemoglobin 9.2g, platelets 190 000, anti “O” 1/333 negative. ESR 110mm / h, serum protein electrophoresis: A53%, α_15.1%, α_221%, β12.2%, γ8.8%. X-ray showed bronchitis. ECG see sinus tachycardia. Admission to use gentamicin, erythromycin,